A survey by the Faculty of Medicine of The Chinese University of Hong Kong (CU Medicine) shows a very low level of acceptance for COVID-19 vaccine among the public in Hong Kong. The projected acceptance rates exhibited a “J-shaped” pattern with age- higher acceptance among young adults (18-24 years), then a decrease in the following age group, and finally a linear increase with age. Government recommendation is the strongest driving force for acceptance, whereas perceived severity instead of perceived susceptibility is associated with acceptance of COVID-19 vaccine. The research team hopes this information could help the Government formulate and implement effective vaccination strategies. The findings have just been presented in Vaccine, an international science journal published by Elsevier.